|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Novel IGHalpha translocations, t(2;14)(q14.3;q32) and t(14;17)(q32;q21), in B-cell precursor acute lymphoblastic leukemia.
|
18656697 |
2008 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Detection of clonotypic IGH and TCR rearrangements in the neonatal blood spots of infants and children with B-cell precursor acute lymphoblastic leukemia.
|
10891460 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
IGH@ translocations co-exist with other primary rearrangements in B-cell precursor acute lymphoblastic leukemia.
|
24816234 |
2014 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
|
17940204 |
2008 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia.
|
19324994 |
2009 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
IGH gene involvement in two cases of acute lymphoblastic leukemia with t(14;14)(q11;q32) identified by sequential R-banding and fluorescence in situ hybridization.
|
15262434 |
2004 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
DNA-based PCR with various sets of primers for TCR gamma/delta, and Ig heavy chain (IgH) genes were used to study clonality in childhood B-lineage acute lymphoblastic leukemia.
|
8086504 |
1994 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here we show that this locus including the gene encoding the telomerase reverse-transcriptase TERT at 5p13.33 is rarely but recurrently targeted by somatic chromosomal translocations to IGH and non-IG loci in B-cell neoplasms, including acute lymphoblastic leukemia, chronic lymphocytic leukemia, mantle cell lymphoma and splenic marginal zone lymphoma.
|
20460502 |
2010 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Lineage conversion from acute lymphoblastic leukemia to acute myeloid leukemia on rearrangement of the IgH gene in a patient with Down syndrome.
|
12138899 |
2002 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis.
|
15010366 |
2004 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The identical IGH-rearrangement in both neoplasms indicates transdifferentiation of the acute B-lymphoblastic leukemia into a Langerhans' cell sarcoma.
|
20421277 |
2010 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Translocation (14;14)(q11;q32) with simultaneous involvement of the IGH and CEBPE genes in B-lineage acute lymphoblastic leukemia.
|
19027493 |
2008 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Clonal immunoglobulin heavy chain (IGH) gene rearrangement is a useful follow-up marker in B-ALL owing to its high positivity rate.
|
28445014 |
2017 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The complementarity determining region (CDR) III of the immunoglobulin heavy-chain (IgH) gene is a tumor-specific marker for B-cell malignancies that has been widely exploited for the monitoring of minimal residual disease in B-precursor acute lymphocytic leukemia.
|
9276186 |
1997 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rearrangement patterns of immunoglobulin heavy chain (IgH) and light chain genes in acute lymphoblastic leukemia and chronic myelocytic leukemia lymphoid crisis cells showing oligoclonal IgH gene rearrangements.
|
1581585 |
1992 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We report on a case of a 30-year-old male with acute B-lymphoblastic leukemia (B-ALL) with immunophenotype CD19(+), CD22(+), CD20(+), CD10(+), with aberrant expression of CD13 and CD117, and IgH gene rearrangements.
|
19143872 |
2009 |