Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE IGH gene involvement in two cases of acute lymphoblastic leukemia with t(14;14)(q11;q32) identified by sequential R-banding and fluorescence in situ hybridization. 15262434 2004
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE IGH@ translocations co-exist with other primary rearrangements in B-cell precursor acute lymphoblastic leukemia. 24816234 2014
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 Biomarker disease BEFREE Clonal immunoglobulin heavy chain (IGH) gene rearrangement is a useful follow-up marker in B-ALL owing to its high positivity rate. 28445014 2017
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE Detection of clonotypic IGH and TCR rearrangements in the neonatal blood spots of infants and children with B-cell precursor acute lymphoblastic leukemia. 10891460 2000
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia. 19324994 2009
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE DNA-based PCR with various sets of primers for TCR gamma/delta, and Ig heavy chain (IgH) genes were used to study clonality in childhood B-lineage acute lymphoblastic leukemia. 8086504 1994
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE Here we show that this locus including the gene encoding the telomerase reverse-transcriptase TERT at 5p13.33 is rarely but recurrently targeted by somatic chromosomal translocations to IGH and non-IG loci in B-cell neoplasms, including acute lymphoblastic leukemia, chronic lymphocytic leukemia, mantle cell lymphoma and splenic marginal zone lymphoma. 20460502 2010
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease BEFREE Lineage conversion from acute lymphoblastic leukemia to acute myeloid leukemia on rearrangement of the IgH gene in a patient with Down syndrome. 12138899 2002
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease LHGDN Novel IGHalpha translocations, t(2;14)(q14.3;q32) and t(14;17)(q32;q21), in B-cell precursor acute lymphoblastic leukemia. 18656697 2008
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 Biomarker disease BEFREE Rearrangement patterns of immunoglobulin heavy chain (IgH) and light chain genes in acute lymphoblastic leukemia and chronic myelocytic leukemia lymphoid crisis cells showing oligoclonal IgH gene rearrangements. 1581585 1992
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease LHGDN t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). 17940204 2008
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 Biomarker disease BEFREE The complementarity determining region (CDR) III of the immunoglobulin heavy-chain (IgH) gene is a tumor-specific marker for B-cell malignancies that has been widely exploited for the monitoring of minimal residual disease in B-precursor acute lymphocytic leukemia. 9276186 1997
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 Biomarker disease BEFREE The identical IGH-rearrangement in both neoplasms indicates transdifferentiation of the acute B-lymphoblastic leukemia into a Langerhans' cell sarcoma. 20421277 2010
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 Biomarker disease BEFREE Translocation (14;14)(q11;q32) with simultaneous involvement of the IGH and CEBPE genes in B-lineage acute lymphoblastic leukemia. 19027493 2008
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 GeneticVariation disease LHGDN Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis. 15010366 2004
Precursor Cell Lymphoblastic Leukemia Lymphoma
0.100 AlteredExpression disease BEFREE We report on a case of a 30-year-old male with acute B-lymphoblastic leukemia (B-ALL) with immunophenotype CD19(+), CD22(+), CD20(+), CD10(+), with aberrant expression of CD13 and CD117, and IgH gene rearrangements. 19143872 2009