Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.060 Biomarker disease BEFREE Additionally, compared to KAI1 and p27 as an individual prognostic marker, the combined signature is more closely associated with melanoma patient survival (P = 0.025, 0.264 and 0.009, respectively). 26246476 2015
CUI: C0025202
Disease: melanoma
melanoma
0.060 GeneticVariation disease BEFREE The p27 Gly protective genotype decreased the risk for melanoma in a stratified analysis of the known risk factors such as hair and eye color, sunburns, pigmented lesions, and European ancestry. 23624368 2013
CUI: C0025202
Disease: melanoma
melanoma
0.060 AlteredExpression disease BEFREE In the latter case, the melanocytoma exhibited an immunophenotype that featured nuclear p27 and no HMB45 staining, with very low Cyclin D1 expression compared with the melanoma that featured little nuclear but more cytoplasmic p27 positivity, much higher Cyclin D1 expression and HMB45 positivity. 23685997 2013
CUI: C0025202
Disease: melanoma
melanoma
0.060 AlteredExpression disease BEFREE The association between GNAQ mutational status, ERK1/2, phospho-ERK1/2, Ki-67, cyclin D1 and p27 expression levels and the clinicopathological prognostic parameters of uveal melanomas was also assessed. 20805136 2011
CUI: C0025202
Disease: melanoma
melanoma
0.060 Biomarker disease BEFREE We also found that Cul1 regulates melanoma cell growth and cell cycle progression through degradation of p27 by functional SCFSkp2 complex. 20878082 2010
CUI: C0025202
Disease: melanoma
melanoma
0.060 AlteredExpression disease BEFREE Targeted cytoplasmic expression of wild-type or non-cdk-binding p27 at subphysiologic levels induced melanoma motility and resulted in numerous metastases to lymph node, lung, and peritoneum. 17909030 2007