FAS, Fas cell surface death receptor, 355

N. diseases: 754; N. variants: 47
Disease: Liver Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 Biomarker disease BEFREE Transplantation of hBMSCs into <i>Fah<sup>-/-</sup>Rag2<sup>-/-</sup>IL-2Rγc<sup>-/-</sup> SCID</i> (FRGS) mice with fulminant hepatic failure (FHF) induced by hamster-anti-mouse CD95 antibody JO2 generated a liver and immune cell dual-humanised (hBMSC-FRGS) mouse. 30700543 2019
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 Biomarker disease BEFREE Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure. 26986512 2016
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 Biomarker disease BEFREE Furthermore, silencing of Fas receptor was effective in blocking or reducing several aspects of ALF when it was tested in mice exposed to galactosamine/lipopolysaccharide (G/L), a well-known model of ALF. 25601293 2015
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 Biomarker disease CTD_human Increased serum soluble Fas in patients with acute liver failure due to paracetamol overdose. 12828076 2003
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 AlteredExpression disease LHGDN Involvement of IL-18 and soluble fas in patients with postoperative hepatic failure. 12679613 2003
CUI: C0162557
Disease: Liver Failure, Acute
Liver Failure, Acute 		0.350 AlteredExpression disease BEFREE CD95 receptor expression was highly elevated in hepatocytes in hepatitis B virus-related cirrhosis (n = 9) and in acute liver failure (n = 8). 7595193 1995