IL1B, interleukin 1 beta, 3553

N. diseases: 1801; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003123
Disease: Anorexia
Anorexia
0.530 Biomarker disease BEFREE Administration of IL-1ß induced fever, lethargy and anorexia for∼two-to-three days and increased the concentration of IL-1ß in the hippocampus and hypothalamus for at least eight hours. 28212946 2017
CUI: C0003123
Disease: Anorexia
Anorexia
0.530 Biomarker disease BEFREE We conclude that the involvement of induced PGE<sub>2</sub> in IL-1β evoked anorexia is strain dependent and we suggest that different routes that probably involve distinct prostanoids exist by which inflammatory stimuli may evoke an anorexic response and that these routes may be of different importance in different strains of mice. 27375005 2017
CUI: C0003123
Disease: Anorexia
Anorexia
0.530 Biomarker disease BEFREE Independently from the presence of anorexia, BOLD signals modification before and after oral challenge correlated with basal values of IL-1 and ghrelin (P < 0.001). 27897393 2017
CUI: C0003123
Disease: Anorexia
Anorexia
0.530 Biomarker disease CTD_human Similar anorectic effects were observed following acute administration of exogenous TNF-α and IL-1β. 25392278 2014
CUI: C0003123
Disease: Anorexia
Anorexia
0.530 Biomarker disease RGD Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats. 22902858 2012