IL1B, interleukin 1 beta, 3553

N. diseases: 1801; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 AlteredExpression disease BEFREE The protective role of Foxp3 in crescentic GN was associated with a markedly suppressed expression of proinflammatory interleukin-1 beta (IL-1β), tumour necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein 1 (MCP-1), and diminished infiltration of the kidneys by CD3<sup>+</sup> T cells and F4/80<sup>+</sup> macrophages. 28469165 2017
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease BEFREE TLR3 expression correlated positively with HCV viral load, interleukin-1β, serum creatinine and inversely with creatinine clearance in patients with HCV-positive glomerulonephritis. 21623661 2011
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease RGD Renoprotective effect of rosuvastatin in DOCA-salt hypertensive rats. 19948880 2010
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease CTD_human Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistant Staphylococcus aureus infection. 10910440 2000
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease BEFREE To address whether these two diseases have a common genetic background, the polymorphism of the variable number tandem repeat (VNTR) of IL-1 receptor antagonist (IL-1ra) gene has been analyzed using PCR in patients diagnosed with HSPN (N = 43) and IgAN (N = 97), together with normal controls (N = 98) and patients with acute post-infectious glomerulonephritis (APGN), under the concept that IL-1 might play an important role in mediating pathogenesis of vasculitis and glomerulonephritis. 9186886 1997
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease CTD_human A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. 9403216 1997
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 AlteredExpression disease BEFREE In segmental sclerosing lesions in FSGS and in IgA-GN with marked glomerular proliferation and/or sclerosis, a reduced expression of the PP-44 antigen and a diminished ability of podocytes to produce IL-1/IL-1 related peptides are noted. 9263995 1997
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis
0.550 Biomarker disease BEFREE In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. 8455368 1993