Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Increased tumor (nuclear) TNFα and IL-1β, CX3CL1 and CXCL1 gene expression was observed in the WLI.Tumor Ki67 did not differ between arms.
|
31442303 |
2020 |
Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Expression of pro-inflammatory cytokines, including tumor necrotic factor-α (TNF-α) and interleukin-1β (IL-1β) were detected using enzyme-linked immunosorbent assay (ELISA) and real time PCR.
|
31678414 |
2020 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Hesperidin treatment in rats with SCI reduced the neuropathological changes (e.g., hemorrhage, inflammatory cell infiltration, and tissue loss) and pro-inflammatory cytokines including tumor necrotic factor-α and interleukin-1β.
|
31715292 |
2020 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
IL-1β, one of the inflammatory cytokines released from myeloid cells in tumor microenvironment, plays an important role in development and progress of tumor.
|
31439870 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Also, the combination therapy of (CUPE + Dox) leads to reducing the levels of serum IL-6, TNF-α, IL-1β and tumor volume compared with untreated tumor-bearing mice and Dox groups.
|
31054317 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Contact between tumor and osteoblasts or bone marrow cells increased IL1B secretion from all three cell types.
|
30670488 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
The low levels of macrophages in IL-1β-deficient mice result in a relatively high percentage of CD11b<sup>+</sup> dendritic cells (DCs) in the tumors.
|
30545915 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
We show that, when human chondrocytes were transfected individually with miR-140-5p, miR-140-3p, or miR-146a prior to stimulation with interleukin-1 beta and tumor factor necrosis-alpha as an inflammatory model of OA, each of these microRNAs exhibited similar protective effects.
|
31446120 |
2019 |
Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Our data reveal the association between genetic polymorphisms of IL-1 and BC susceptibility in the Chinese Han population and indicates that IL-1 polymorphisms are closely associated with tumor markers and IL-1β protein expression in BC patients.
|
31297985 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
We measured disease activity (weight loss, stool consistency, fecal occult blood) during the study and at sacrifice, collected blood for cytokine/biomarker (Ang2, interleukin [IL] 1-β, IL-6, tumor necrosis factor α [TNFα], and VEGF-C) enzyme-linked immunosorbent assay analysis, measured colon length, and assessed tumor burden.
|
31173626 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Tumor-supplied IL1β contributes to adipocyte lipolysis and regulates a proinflammatory phenotype in adipocytes via upregulation of COX-2 and MCP-1.
|
31562254 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
IL-37 is a cytokine of IL-1 family that plays an important role in innate immunity and inflammation, and has been studied as a tumor suppressor in many cancers.
|
31410060 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Pharmacological inhibition of PGE2 biosynthesis in EGCs or IL-1 knockdown in tumor epithelial cells prevented EGC acquisition of a pro-tumorigenic phenotype.
|
31662289 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Interleukin-1 receptor type 2 (IL1R2) is a decoy receptor for IL-1 cytokines and involved in host inflammatory and immune progression which could lead to the lesion and neoplasia of cervix.
|
30460760 |
2019 |
Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
However, hippocampal mRNA expression of major proinflammatory cytokines IL-1β and TNFα was increased in tumor removal animals, persisting past surgical recovery.
|
30496733 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
IL-1β sustains tumor growth recovery in 5-FU-treated mice.
|
31217433 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
L2-IL1B mice fed an HFD developed esophageal dysplasia and tumors more rapidly than mice fed the control diet; the speed of tumor development was independent of body weight.
|
30998992 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
This opportunity is investigated by comparing the membrane protein composition and the tumor uptake of NGs derived from naïve MSCs (N-NG) against conditioned NGs made from MSCs pre-treated with conditioned-media (CM-NG) or with a mix of the proinflammatory cytokines TNF-α and IL-1β (Cyto-NG).
|
30963725 |
2019 |
Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Specifically in CC-group, a positive correlation was found between ANGPTL-4 levels and those of IL-1β, TNF-α, and NFκB in tumor, along with an association between ANGPTL-4 levels with IL-1β and MCP-1 levels in tumor; and ANGPTL-4 and IL-1β levels in MES.
|
31741709 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
The modulatory role of the Bifidobacterium longum (BL), isolated from women breast milk, on some oncogenic and tumor suppressor miRNAs as well as IL-1β and IL6 targeted-miRNAs was investigated using murine colorectal cancer (CRC) induced on the top of inflammatory ulcerative colitis model.
|
30862187 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Proteomic analysis revealed that enrichment of IL1β and TNFα in stage IV human tumor microenvironments was associated with a worse prognosis.
|
30545920 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Colonic tumor biomarker analysis revealed that proliferation (proliferating cell nuclear antigen and p21), apoptosis (p53 and Caspase-3), and proinflammatory mediators (IL1β and prostaglandin E<sub>2</sub>) were significantly correlated with the tumor inhibitory effects of aspirin and naproxen.
|
31530543 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
We showed that both chemokines (CXCL12, IP-10, and CCL27) and cytokines profiles (IL-1β and IL-6) were altered in the tumor microenvironment and might reduce NK cell function and recruitment to the tumor site.
|
31105699 |
2019 |
Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
We show in vitro that IL-1α and IL-1β released by pancreatic cancer cells and tumor cell-conditioned macrophages are crucial for TSLP secretion by CAFs.
|
30760333 |
2019 |
Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Tnf-α, Il-1β, and Il-6 mRNA decreased in multiple brain regions of LPS-treated tumor-bearing mice relative to LPS-treated controls; tumor resection attenuated these effects in some cases (but not Tnf-α).
|
30679700 |
2019 |