IL2, interleukin 2, 3558

N. diseases: 950; N. variants: 5
Disease: Autoimmune Chronic Hepatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.340 GeneticVariation disease BEFREE G/T alleles of IL-2 at -330 (rs2069762) and A/T alleles on UTR +5644 position at IFN-γ and their subsequent haplotypes, did not show significant association with AIH. 29288086 2018
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.340 Biomarker disease BEFREE Baseline IL-2 and the AIH score can predict the response to standard therapy in paediatric autoimmune hepatitis. 29323192 2018
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.340 Biomarker disease BEFREE Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy. 28700730 2017
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.340 Biomarker disease CTD_human Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats. 21227906 2011
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.340 Biomarker disease BEFREE Purified CD4+CD25+ and CD4+CD25- T cells from 24 patients with type 1 AIH and 22 healthy controls were cultured for up to 5 weeks with anti-CD3/anti-CD28 T cell expander and high-dose interleukin-2 (IL-2). 18220288 2008