IL6ST, interleukin 6 signal transducer, 3572

N. diseases: 260; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.310 Biomarker disease BEFREE Genetic reduction of Stat3 hyperactivity in gp130(F/F):Stat3(-/+) mice prevented lung inflammation and excessive protease activity; however, emphysema still developed. 22268122 2012
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.310 Biomarker disease CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011