Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE A colorimetric microarray for the multiplexed detection of recurrence of bladder cancer including protein markers interleukin-8 (IL8), decorin (DCN), and vascular endothelial growth factor (VEGF) was established to enable easy and cheap read-out by a simple office scanner paving the way for quick therapy monitoring at doctors' offices. 29364182 2018
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE Together, these results demonstrate the key roles of B cells within the bladder tumor microenvironment that increase the BCa metastasis and may help us to develop the potential therapies via targeting these newly identified IL-8/AR/MMPs signals to better battle the BCa progression. 26305549 2015
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE TNF-α, IL-6 and IL-8 have been shown to be involved in the development and progression of various cancers, including bladder cancer. 23727622 2013
Malignant neoplasm of urinary bladder
0.400 AlteredExpression disease BEFREE Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer. 22695075 2012
Malignant neoplasm of urinary bladder
0.400 Biomarker disease CTD_human Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells. 22015448 2012
Malignant neoplasm of urinary bladder
0.400 GeneticVariation disease BEFREE IL-8 -251 T > A polymorphism is associated with bladder cancer susceptibility and outcome after BCG immunotherapy in a northern Indian cohort. 20470938 2010
Malignant neoplasm of urinary bladder
0.400 AlteredExpression disease BEFREE These findings indicate that at the early stage of tumor growth, bFGF and IL-8 expression play important roles in the regulation of angiogenesis, tumorigenicity and subsequent metastases of human bladder cancer. 19096229 2008
Malignant neoplasm of urinary bladder
0.400 GeneticVariation disease BEFREE Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G-->C), IL-8 (-251 T-->A), tumor necrosis factor-alpha (TNF-alpha; -308 G-->A), and peroxisome proliferator-activated receptor gamma (PPARG; Pro12Ala), and determined their associations with BC initiation and clinical outcome. 16110031 2005
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE Nuclear factor-kappaB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8. 12855659 2003
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE Adenoviral-mediated gene therapy of human bladder cancer with antisense interleukin-8. 11496299 2001
Malignant neoplasm of urinary bladder
0.400 AlteredExpression disease BEFREE Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer. 10786697 2000
Malignant neoplasm of urinary bladder
0.400 Biomarker disease BEFREE In the present manuscript, we identify the factors constitutively produced by a human bladder cancer cell line (KU-19-19) that was found to produce beta human chorionic gonadotrophin (beta-hCG), granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 1alpha (IL-1alpha), interleukin 6 (IL-6) and interleukin 8 (IL-8). 9231915 1997