IL10, interleukin 10, 3586

N. diseases: 1679; N. variants: 21
Disease: Abscess ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0000833
Disease: Abscess
Abscess 		0.010 GeneticVariation phenotype BEFREE Moreover, severe infantile enterocolitis resembling Crohn's disease, caused by loss-of-function mutations in IL-10 and IL-10 receptor, is characterised by a very early onset (usually within the first 3 months of life), unresponsiveness to standard treatment including immunosuppressive therapy, and severe perianal disease with abscesses and fistulas. 25004811 2014