AQP3, aquaporin 3 (Gill blood group), 360

N. diseases: 124; N. variants: 1
Disease: Dermatitis, Atopic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.040 AlteredExpression disease BEFREE When the expression level of AQP3 was elevated, impaired barrier integrity and increased pro-inflammatory cytokine production ensued, mimicking the pathological conditions in Notch deficient mice and in atopic dermatitis. 24260356 2013
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.040 Biomarker disease BEFREE However, the involvement of AQP3 in epidermal hyperplasia in skin diseases, such as atopic dermatitis (AD), is unknown. 21191421 2011
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.040 AlteredExpression disease BEFREE AQP3 expression in human skin is increased in response to skin stress in diseases such as atopic eczema, to various agents such as retinoic acid, and in skin carcinomas. 18548108 2008
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.040 AlteredExpression disease LHGDN By contrast, in acute and chronic atopic eczema strong AQP3 staining was found in both the stratum basale and the stratum spinosum. 16918518 2006
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		0.040 AlteredExpression disease BEFREE Increased expression of aquaporin 3 in atopic eczema. 16918518 2006