IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.330 GeneticVariation group BEFREE Our results suggest that IL-18 -137 G/C polymorphism is significantly associated with the progression of oral cancer but -607 C/A polymorphism is not associated with this. 25398690 2014
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.330 GeneticVariation group BEFREE The participants with G/C heterozygotes of IL-18 -137 polymorphism had a 1.64-fold (95% CI: 1.08-2.48; p=0.02) increased risk of developing oral cancer compared with those with G/G wild type homozygotes. 24349532 2013
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.330 Biomarker group CTD_human Impact of interleukin-18 polymorphisms -607A/C and -137G/C on oral cancer occurrence and clinical progression. 24349532 2013
CUI: C0153381
Disease: Malignant neoplasm of mouth
Malignant neoplasm of mouth
0.330 GeneticVariation group BEFREE The interleukin-18 -607A/C polymorphism is not associated with risk for oral cancer. 18225563 2008