Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
Interleukin-18 (IL-18) is a proinflammatory cytokine associated with metabolic syndrome (MS).
|
29854715 |
2018 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
Inflammasomes, which are intracellular multi-protein complexes, promote acute and chronic inflammation via interleukin-1β or interleukin-18 maturation, and they are known targets for metabolic syndromes and cancer.
|
27133472 |
2018 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
Conversely, a non-significant increase in IL-18 was observed in the MetS and MetS pre/T2DM groups compared to normoglycaemic lean controls (232 and 287.5, <i>p</i> > 0.05 versus 108 for both).
|
30515292 |
2018 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
Interleukin-18 (IL-18) is an inflammatory cytokine found to be elevated in obesity, metabolic syndrome and type 2 diabetes (T2D) as a part of the chronic low-grade inflammatory process in these states.
|
29217651 |
2018 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
The control group consisted of 33 men without MS and low T. IL-18 was determined in serum using enzyme-linked immunosorbent assay.
|
29168426 |
2018 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
BEFREE |
Susceptibility disorders for AD, including obesity, type-2 diabetes, cardiovascular diseases and metabolic syndrome have been linked to increases in the proinflammatory cytokine, IL-18, which also regulates multiple AD related proteins.
|
28531131 |
2017 |
Metabolic Syndrome X
|
0.600 |
Therapeutic
|
disease |
RGD |
Betaine supplementation protects against high-fructose-induced renal injury in rats.
|
24456735 |
2014 |
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Multivariate analysis revealed fasting plasma glucose to be the only MetS component being independently associated with expression of IL-18 in AT (p < 0.05).
|
21842238 |
2011 |
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
IL-18 levels were significantly higher in men as compared to women, and in patients with diabetes type 2 and metabolic syndrome compared to those without (p ≤ 0.001, all).
|
22141572 |
2011 |
Metabolic Syndrome X
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated variation within the IL18 gene and its association with measures of obesity and the metabolic syndrome.
|
20227263 |
2011 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
RGD |
Targeting expression of IL-18 or its specific downstream mediators may retard the progression of MetS and its complications.
|
19717152 |
2010 |
Metabolic Syndrome X
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated variation within the IL18 gene and its effect on markers of the metabolic syndrome.
|
17445542 |
2007 |
Metabolic Syndrome X
|
0.600 |
Biomarker
|
disease |
CTD_human |
Effect of rosiglitazone on endothelial function and inflammatory markers in patients with the metabolic syndrome.
|
16644639 |
2006 |