CXCL10, C-X-C motif chemokine ligand 10, 3627

N. diseases: 631; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.340 Biomarker disease BEFREE The role of CXCR3 and its ligands CXCL10 and CXCL11 in the pathogenesis of celiac disease. 31232926 2019
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.340 AlteredExpression disease BEFREE TG2-specific compared to non-TG2 specific PCs expressed increased levels of CXCR3, CXCL10 and interleukin-15; factors that have been implicated in the pathogenesis of CeD yet with production attributed to other cells than PCs. 31839965 2019
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.340 Biomarker disease BEFREE Selected biomarkers were able to classify subjects with clear CD/non-CD status, and a subset of the biomarkers (CXCL10, GBP5, IFI27, IFNG, and UBD) showed differential expression in biopsies from subjects with no or low-grade intestinal injury that received a CD diagnosis based on biopsies taken at a later time point. 30097691 2018
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.340 AlteredExpression disease BEFREE Increased IFN-γ and IP-10 levels after challenge were observed in patients with CD, but not in controls. 29903545 2018
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.340 Biomarker disease CTD_human Selected biomarkers were able to classify subjects with clear CD/non-CD status, and a subset of the biomarkers (CXCL10, GBP5, IFI27, IFNG, and UBD) showed differential expression in biopsies from subjects with no or low-grade intestinal injury that received a CD diagnosis based on biopsies taken at a later time point. 30097691 2018