INSM1, INSM transcriptional repressor 1, 3642

N. diseases: 85; N. variants: 1
Disease: Herpes Simplex Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.020 Biomarker group BEFREE In the present study, we analyzed the therapeutic potential of an adenoviral INSM1 promoter-driven herpes simplex virus thymidine kinase (HSV-tk) construct in primitive neuroectodermal tumors (PNETs). 19604042 2009
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.020 AlteredExpression group BEFREE Expression of the suicide gene herpes simplex virus thymidine kinase (HSV-TK) from the INSM1 promoter in combination with treatment with the prodrug ganciclovir (GCV) caused a significant increase in GCV sensitivity specifically in INSM1-expressing cell lines. 16052225 2006