INSM1, INSM transcriptional repressor 1, 3642

N. diseases: 85; N. variants: 1
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.030 Biomarker group BEFREE The sensitivity of INSM1 for neuroendocrine lung neoplasms as a group (95%) was similar to synaptophysin (98%) and CD56 (97%), but higher than chromogranin (84%). 30154579 2019
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.030 Biomarker group BEFREE INSM1 was positive in 48 of 52 primary lung neuroendocrine neoplasms (92%), including 38 of 41 SCLCs (93%), the only LCNEC (100%), and 9 of 10 carcinoid tumors (90%), and it was negative in all 22 non-neuroendocrine primary lung tumors. 29360191 2018
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.030 Biomarker group BEFREE In a mouse subcutaneous xenograft tumor model, the combination viruses secreted detectable level of Gaussia luciferase after infecting an INSM1-positive NE lung tumor for ≥12 days. 26530405 2016