INSR, insulin receptor, 3643

N. diseases: 452; N. variants: 109
Disease: Migrating partial seizures in infancy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3494976
Disease: Migrating partial seizures in infancy
Migrating partial seizures in infancy 		0.010 Biomarker disease BEFREE The HIRMAb domain binds the endogenous insulin receptor on the human BBB to trigger receptor-mediated transport across the BBB, and acts as a molecular Trojan horse to ferry the fused IDUA into the brain of patients with MPSI. 29442294 2018