|
Endometriosis of uterus
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate whether eIF3e is involved in EMT in adenomyosis.
|
29871559 |
2019 |
|
Traditional Serrated Adenoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The present study identified EIF3E-RSPO2 and PIEZO1-RSPO2 in TSAs.
|
30916365 |
2019 |
|
Colorectal Traditional Serrated Adenoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.
|
30916365 |
2019 |
|
Eclampsia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Int6 silencing alleviated the maternal clinical manifestations of pre-eclampsia and promoted placental angiogenesis in pregnant L-NAME-treated rats.
|
29895936 |
2018 |
|
Endometriosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate whether eIF3e is involved in EMT in endometriosis.
|
28438065 |
2018 |
|
Squamous cell carcinoma of esophagus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<b>Methods</b>: Immunohistochemical staining and Western blot were performed to detect the eIF3e expression in ESCC patients' tissues.
|
29675094 |
2018 |
|
Extrapulmonary Small Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<b>Methods</b>: Immunohistochemical staining and Western blot were performed to detect the eIF3e expression in ESCC patients' tissues.
|
29675094 |
2018 |
|
Vascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Although a deeper understanding of the molecular mechanisms involved in these pathophysiological functions is essential, particularly to transform the <i>in vitro</i>/<i>in vivo</i> findings into clinical applications, INT6/eIF3e modulation could provide therapeutic benefit for a variety of human diseases such as cancer or vascular diseases.
|
27814599 |
2017 |
|
Malignant neoplasm of urinary bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our study indicates that NONHSAG013805 and NONHSAG009271 may play key roles in bladder cancer via co-expressing with EIF3E and MYL12A, respectively.
|
27451077 |
2016 |
|
Bladder Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our study indicates that NONHSAG013805 and NONHSAG009271 may play key roles in bladder cancer via co-expressing with EIF3E and MYL12A, respectively.
|
27451077 |
2016 |
|
Carcinoma of bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our study indicates that NONHSAG013805 and NONHSAG009271 may play key roles in bladder cancer via co-expressing with EIF3E and MYL12A, respectively.
|
27451077 |
2016 |
|
Limb ischemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Silencing of eIF3e promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2α activity.
|
25758454 |
2016 |
|
Carcinoma of lung
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Decreased eIF3e expression is often observed in breast and lung cancer and has been shown to induce epithelial-to-mesenchymal transition (EMT) in breast epithelial cells by an unknown mechanism.
|
26056130 |
2015 |
|
Primary malignant neoplasm of lung
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Decreased eIF3e expression is often observed in breast and lung cancer and has been shown to induce epithelial-to-mesenchymal transition (EMT) in breast epithelial cells by an unknown mechanism.
|
26056130 |
2015 |
|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Taken together, high eIF3e expression may contribute to tumor progression and predict poor prognosis in colon cancer.
|
25400724 |
2014 |
|
Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The functional significance of Int6 and the effect of Int6/EIF3E gene silencing on human brain GBM has not yet been described and its role on the HIFs is unknown in glioma cells.
|
24481065 |
2014 |
|
Adult Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Int6/eIF3e is essential for proliferation and survival of human glioblastoma cells.
|
24481065 |
2014 |
|
Childhood Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Int6/eIF3e is essential for proliferation and survival of human glioblastoma cells.
|
24481065 |
2014 |
|
Secondary malignant neoplasm of lymph node
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of eIF3e was significantly elevated in colon cancer tissues in comparison with those in adjacent normal mucosa (P < 0.001) and lymph node metastasis (P < 0.001).
|
25400724 |
2014 |
|
Colon Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Taken together, high eIF3e expression may contribute to tumor progression and predict poor prognosis in colon cancer.
|
25400724 |
2014 |
|
Glioblastoma Multiforme
|
0.010 |
Biomarker
|
disease |
BEFREE |
Int6/eIF3e is essential for proliferation and survival of human glioblastoma cells.
|
24481065 |
2014 |
|
Malignant transformation
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Reduced expression of eIF3e/Int6 has been found in up to 37% of human breast cancers, and expression of a truncated mutant version of the mouse eIF3e/Int6 protein leads to malignant transformation of normal mammary cells.
|
22907435 |
2013 |
|
Precancerous Conditions
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Microarray analyses were performed on normal, premalignant and malignant WapInt6sh expressing tissues.
|
17626637 |
2007 |
|
Mammary Tumorigenesis
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
These observations provide direct in vivo evidence that mammary-specific expression of the Int6sh truncation leads to persistence of alveolar hyperplasia with the accompanying increased predisposition to mammary tumorigenesis.
|
17626637 |
2007 |
|
stage, non-small cell lung cancer
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Int6 expression can predict survival in early-stage non-small cell lung cancer patients.
|
15867213 |
2005 |