IRF1, interferon regulatory factor 1, 3659

N. diseases: 257; N. variants: 7
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 Biomarker disease BEFREE MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling. 31186404 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 Biomarker disease BEFREE MTMR2 mediated EMT through the IFNγ/STAT1/IRF1 pathway to promote GC invasion and metastasis. 31113461 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 GeneticVariation disease BEFREE SNP rs56288038 (C/G) in IRF-1 3'UTR was involved in the occurrence of GC by acting as a tumor promoter factor. 27866197 2016
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 Biomarker disease BEFREE We used these clones and recombinant adenovirus expressing IRF-1 to explore the mechanism of IRF-1-induced apoptosis in gastric cancer. 19851330 2010
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 GeneticVariation disease UNIPROT Interferon regulatory factor 1 tryptophan 11 to arginine point mutation abolishes DNA binding. 10395927 1999
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 GeneticVariation disease UNIPROT Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer. 9679752 1998
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 GeneticVariation disease BEFREE Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer. 9679752 1998
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 Biomarker disease GENOMICS_ENGLAND
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.650 CausalMutation disease CGI