IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.030 AlteredExpression disease BEFREE DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes. 23490285 2013
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.030 Biomarker disease BEFREE Notably, this network showed strong overlap with a recently discovered IRF7-driven network relevant to Type 1 diabetes. 23386205 2013
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.030 GeneticVariation disease BEFREE These data implicate IRF7 network genes and their regulatory locus in the pathogenesis of T1D. 20827270 2010