IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Epstein-Barr Virus Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149678
Disease: Epstein-Barr Virus Infections
Epstein-Barr Virus Infections 		0.030 Biomarker group BEFREE Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein-Barr virus (EBV) infection, and has since emerged as the crucial regulator of type I interferons (IFNs) against pathogenic infections, which activate IRF7 by triggering signaling cascades from pathogen recognition receptors (PRRs) that recognize pathogenic nucleic acids. 21490621 2011
CUI: C0149678
Disease: Epstein-Barr Virus Infections
Epstein-Barr Virus Infections 		0.030 Biomarker group BEFREE However, its dual ubiquitin-editing activities have not been investigated in the context of either EBV infection or IRF7 responses. 20392859 2010
CUI: C0149678
Disease: Epstein-Barr Virus Infections
Epstein-Barr Virus Infections 		0.030 Biomarker group BEFREE IRF-7 appears to be a key cellular latency protein involved in both the pathogenesis and persistence of EBV infection. 11669606 2001