IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Lupus Erythematosus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.030 Biomarker disease BEFREE The type-I interferon master regulator gene IRF7 is only hypomethylated in lupus patients with renal involvement. 26005050 2015
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.030 AlteredExpression disease BEFREE Compared with controls, the expression of IRF7 mRNA was significantly increased in patients with SLE and was positively correlated with both the serum level of IFN-α and lupus disease activity. 21632682 2011
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.030 AlteredExpression disease BEFREE Western blot analysis showed that induction of IRF7 protein expression correlated with recurrent lupus disease activity. 21576205 2011