IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Disease: Influenza A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE However, the deficiency of IRF7 increases the susceptibility to deadly IAV infection in both humans and mice. 30667045 2019
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 AlteredExpression disease BEFREE The results showed that IAV infection led to low body weight and high viral load and high expression of RIG-I, IRF3, IRF7, and NF-<i>κ</i>B mRNA, as well as RIG-I and NF-<i>κ</i>B p65 protein. 29681974 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.030 Biomarker disease BEFREE Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection. 27811478 2017