IRF7, interferon regulatory factor 7, 3665

N. diseases: 121; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.020 AlteredExpression disease BEFREE We found that HIV-1 infection also induced interferon regulatory factor (IRF)-1, IRF-7 gene expression and signal transducers and activators of transcription 1 (STAT1) activation. 19404407 2009
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.020 Biomarker disease BEFREE The lack of response associated with a marked depletion of IRF-3 but not IRF-7 in HIV-1-infected cells, which supported robust viral replication, whereas ectopic expression of active IRF-3 suppressed HIV-1 infection. 19706707 2009