ITGB1, integrin subunit beta 1, 3688

N. diseases: 210; N. variants: 4
Disease: Cardiomyopathy, Familial Idiopathic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1449563
Disease: Cardiomyopathy, Familial Idiopathic
Cardiomyopathy, Familial Idiopathic 		0.310 Biomarker disease BEFREE In conclusion, our results demonstrate that c-Cbl mediates the ubiquitination/degradation of integrin β1, which leads to COMP deficiency-induced DCM. 27693578 2016
CUI: C1449563
Disease: Cardiomyopathy, Familial Idiopathic
Cardiomyopathy, Familial Idiopathic 		0.310 Biomarker disease CTD_human Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. 11884376 2002