ITGB3, integrin subunit beta 3, 3690

N. diseases: 260; N. variants: 44
Disease: Prostatic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 Biomarker group LHGDN Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. 18512729 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 AlteredExpression group LHGDN Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells. 17034033 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 AlteredExpression group LHGDN Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling. 17369840 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 Biomarker group CTD_human [Prognostic implications of GP3a glucoprotein gene PLA1/PLA2 allele in prostatic cancer: pilot results of the study]. 16158739 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 Biomarker group LHGDN Inhibition of alpha(v)beta3 integrin reduces angiogenesis, bone turnover, and tumor cell proliferation in experimental prostate cancer bone metastases. 14524530 2003
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 AlteredExpression group LHGDN Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration. 12771130 2003
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.360 AlteredExpression group LHGDN Role of the orphan nuclear receptor ROR alpha in the control of the metastatic behavior of androgen-independent prostate cancer cells. 12168086 2003