Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group LHGDN Critical role of c-Jun overexpression in liver metastasis of human breast cancer xenograft model. 17672916 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group LHGDN The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors. 17637753 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group LHGDN Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer. 14654548 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group BEFREE We studied the expression of AP-1 members at the mRNA level in 72 primary breast tumors and 37 adjacent non-tumor tissues and evaluated its correlation with clinicopathological parameters including estrogen receptor (ER), progesterone receptor (PR) and HER2/neu status. 24073962 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 Biomarker group BEFREE In addition, Ad-MMP-9, in combination with radiation, decreased levels of the transcription factors nuclear factor-kappaB and activator protein 1, both of which contribute to the radioresistance of breast tumors. 18519796 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 Biomarker group BEFREE Our studies in a cohort of human breast tumors identified PR and AP-1 nuclear interaction as a marker of good prognosis and better OS in patients treated with tamoxifen (Tam), an anti-estrogen receptor therapy. 24345432 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 Biomarker group CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group LHGDN c-Jun, a crucial molecule in metastasis of breast cancer and potential target for biotherapy. 17914574 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 AlteredExpression group LHGDN Prolactin and estrogen enhance the activity of activating protein 1 in breast cancer cells: role of extracellularly regulated kinase 1/2-mediated signals to c-fos. 15746191 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.390 Biomarker group BEFREE Alternative Polyadenylation in Triple-Negative Breast Tumors Allows NRAS and c-JUN to Bypass PUMILIO Posttranscriptional Regulation. 27758885 2016