KARS1, lysyl-tRNA synthetase 1, 3735

N. diseases: 62; N. variants: 13
Disease: Multiple Chronic Conditions ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions 		0.030 Biomarker disease BEFREE Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex. 30733335 2019
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions 		0.030 Biomarker disease BEFREE Syntenin bound to the exposed PDZ-binding motif of KRS and facilitated the exosomic secretion of KRS dissociated from the multi-tRNA synthetase complex. 28611052 2017
CUI: C3266262
Disease: Multiple Chronic Conditions
Multiple Chronic Conditions 		0.030 Biomarker disease BEFREE LysRS is normally sequestered in a multi-aminoacyl-tRNA synthetase complex (MSC). 28814526 2017