AREG, amphiregulin, 374

N. diseases: 221; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease BEFREE The immunopathology of lung fibrosis: amphiregulin-producing pathogenic memory T helper-2 cells control the airway fibrotic responses by inducing eosinophils to secrete osteopontin. 30968186 2019
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease CTD_human Last, the in vivo silencing efficacy of SAMiRNAs was evaluated by targeting amphiregulin and connective tissue growth factor in bleomycin or TGF-β transgenic animal models of pulmonary fibrosis. 26817844 2016
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease BEFREE Little is known about the roles of amphiregulin in lung injury and pulmonary fibrosis. 19915156 2010
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.330 Biomarker disease BEFREE These data suggest that local release of amphiregulin by human mast cells could play an important role in lung fibrosis by promoting the proliferation of primary human lung fibroblasts. 15696083 2005