KCP, kielin cysteine rich BMP regulator, 375616

N. diseases: 6; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure
0.010 Biomarker disease BEFREE However, the role of KCP during heart failure (HF) remains unknown. 30144436 2018
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.010 Biomarker disease BEFREE However, the role of KCP during heart failure (HF) remains unknown. 30144436 2018
CUI: C0028754
Disease: Obesity
Obesity
0.010 AlteredExpression disease BEFREE In contrast, transgenic mice that expressed KCP in the kidney, liver, and adipose tissues were resistant to developing high-fat diet-induced obesity and had significantly reduced white adipose tissue. 28424263 2017
CUI: C0271650
Disease: Impaired glucose tolerance
Impaired glucose tolerance
0.010 Biomarker phenotype BEFREE KCP loss sensitized the mice to obesity and associated complications such as glucose intolerance and adipose tissue inflammation and fibrosis. 28424263 2017
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.010 Biomarker disease BEFREE The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. 28424263 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker disease BEFREE Factors involved in the cisplatin resistance of KCP‑4 human epidermoid carcinoma cells. 24317338 2014