Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042834
Disease: Vital capacity
Vital capacity
0.100 GeneticVariation phenotype GWASCAT New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. 30804560 2019
CUI: C0042834
Disease: Vital capacity
Vital capacity
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.320 Biomarker disease BEFREE KCNS3 and LHX6 might be useful for characterizing cell-type specific molecular alterations of cortical GABA neurotransmission and for the development of novel treatments targeting PV and/or SST neurons in schizophrenia. 22937123 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.320 AlteredExpression disease BEFREE By in situ hybridization, KCNS3 mRNA levels were 23% lower in schizophrenia subjects. 24170294 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.320 Biomarker disease PSYGENET By in situ hybridization, KCNS3 mRNA levels were 23% lower in schizophrenia subjects. 24170294 2014
CUI: C1518922
Disease: peak expiratory flow (procedure)
peak expiratory flow (procedure)
0.100 GeneticVariation phenotype GWASCAT New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. 30804560 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.010 AlteredExpression disease BEFREE Because impaired prefrontal cortical γ-oscillations are thought to underlie the cognitive impairments in schizophrenia, the authors investigated whether KCNS3 mRNA levels are altered in the prefrontal cortex of schizophrenia subjects. 24170294 2014
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function
0.100 GeneticVariation phenotype GWASCAT Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. 26635082 2015
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function
0.100 GeneticVariation phenotype GWASCAT Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. 28166213 2017
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function
0.100 GeneticVariation phenotype GWASCAT New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. 30804560 2019
CUI: C0004096
Disease: Asthma
Asthma
0.010 Biomarker disease BEFREE Thus, the gene encoding the potassium voltage-gated channel delayed-rectifier protein S3 (KCNS3) in this region is considered a positional candidate for asthma. 15714333 2005