KNG1, kininogen 1, 3827

N. diseases: 279; N. variants: 24
Disease: Acquired angioedema ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2931758
Disease: Acquired angioedema
Acquired angioedema 		0.340 Biomarker disease BEFREE Acquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. 31397881 2019
CUI: C2931758
Disease: Acquired angioedema
Acquired angioedema 		0.340 Biomarker disease BEFREE Acquired C1 inhibitor (C1-INH) deficiency exposes patients to angioedema recurrences (acquired angioedema [AAE]) mediated by bradykinin pathway activation. 23406939 2013
CUI: C2931758
Disease: Acquired angioedema
Acquired angioedema 		0.340 Biomarker disease BEFREE A review was conducted of scientific papers on different types of bradykinin-induced angioedema (hereditary and acquired angioedema due to C1 inhibitor deficiency, hereditary angioedema related to estrogens, angioedema induced by angiotensin-converting enzyme inhibitors). 21905496 2011
CUI: C2931758
Disease: Acquired angioedema
Acquired angioedema 		0.340 Biomarker disease CTD_human Plasma bradykinin in angio-oedema. 9734886 1998
CUI: C2931758
Disease: Acquired angioedema
Acquired angioedema 		0.340 Biomarker disease BEFREE During remission, cleaved HK was normal in HAE and high in AAE; during attacks it increased in HAE (P = .0008) and remained elevated in AAE. 9129025 1997