ARG1, arginase 1, 383

N. diseases: 273; N. variants: 47
Disease: Leishmaniasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis 		0.310 AlteredExpression disease BEFREE Moreover, Leishmania infection triggered cell proliferation as was evidenced by increased expression of cyclin A and p-RPS6. mTOR activation during Leishmania infection resulted in reduced expression of M1 macrophage markers (eg, ROS, NO, iNOS, NOX-1, IL-12, IL-1β and TNF-α), and increased expression of M2 macrophage markers (eg, arginase-1, IL-10, TGF-β, CD206 and CD163). 30187512 2018
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis 		0.310 Biomarker disease CTD_human Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I. 21232540 2011