RHOA, ras homolog family member A, 387

N. diseases: 193; N. variants: 16
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.320 Biomarker disease BEFREE Recent genetic analysis has identified frequent mutations in ten-eleven translocation 2 (TET2), DNA methyltransferase 3A (DNMT3A), isocitrate dehydrogenase 2 (IDH2) and ras homolog family member A (RHOA) in nodal T-cell lymphomas, including angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, not otherwise specified. 28157189 2017
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.320 Biomarker disease CTD_human Our experimental data and modeling results suggest that the RHOA mutation encoding p.Gly17Val is a driver mutation in AITL. 24584070 2014
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.320 GeneticVariation disease BEFREE Further examination of the RHOA mutation encoding p.Gly17Val in 239 lymphoma samples showed that the mutation was specific to T cell lymphoma and was absent from B cell lymphoma. 24584070 2014