Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To compare the published results of studies on the genotype association of ARMS2/LOC387715 A69S, CFH Y402H, and CFH I62V in cases diagnosed as retinal angiomatous proliferation (RAP) versus neovascular age-related macular degeneration (AMD) or healthy controls.
|
28005184 |
2017 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
In the subgroup with genotype data, ARMS2 rs10490924 and CFH rs800292 were associated with nAMD.
|
28120909 |
2017 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
ARMS2 A69S polymorphism is associated with the number of ranibizumab injections needed for exudative age-related macular degeneration in a pro re nata regimen during 4 years of follow-up.
|
28744656 |
2017 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of neovascular age-related macular degeneration in the Thai population.
|
28703135 |
2017 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Effect of ARMS2 gene polymorphism on intravitreal ranibizumab treatment for neovascular age-related macular degeneration.
|
28002601 |
2016 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
GWASCAT |
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
|
26691988 |
2016 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
GWASCAT |
New loci and coding variants confer risk for age-related macular degeneration in East Asians.
|
25629512 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
CFH Y402H and ARMS2 A69S Polymorphisms and Oral Supplementation with Docosahexaenoic Acid in Neovascular Age-Related Macular Degeneration Patients: The NAT2 Study.
|
26132079 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
Biomarker
|
disease |
BEFREE |
In this study, we found that the interaction of ARMS2 and ARMS2/HTRA1 is significantly associated with nAMD, and the interaction of CFH and ARMS2 is pronounced in PCV development in Chinese population.
|
25771815 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Association of Smoking and CFH and ARMS2 Risk Variants With Younger Age at Onset of Neovascular Age-Related Macular Degeneration.
|
25695752 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Twelve polymorphisms at the ARMS2-HTRA1 locus showed significant differences between PCV and nAMD.
|
26081444 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
A study was undertaken to investigate the association between A69S in age-related maculopathy susceptibility 2 (ARMS2) and the response to anti-angiogenesis treatment in exudative age-related macular degeneration (AMD).
|
25185256 |
2015 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
This study revealed significant relationships between the plasma MDA level and ARMS2 variants and phenotypes in PCV and nAMD.
|
24240564 |
2014 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Gene-gene interactions of CFH and LOC387715/ARMS2 with Korean exudative age-related macular degeneration patients.
|
23289807 |
2013 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
After adjusting for rs11200638, ARMS2 rs10490924 remained significantly associated with nAMD and PCV (p<0.001).
|
23326481 |
2013 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The variants in CFH, ARMS2 and near HTRA1 were strongly associated with both PCV (P < 10(-6), 10(-7) and 10(-7) respectively) and nAMD (P < 10(-6), 10(-16) and 10(-17) respectively).
|
23274582 |
2013 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Three previously reported associations of response to VEGF inhibition in nAMD involving single nucleotide polymorphisms (SNPs) at the CFH, FZD4, and HTRA1/ARMS2 loci were tested for replication.
|
24070809 |
2013 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
differentiate the associations of exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) with the ARMS2/HTRA1 locus.
|
22491416 |
2012 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland - a brief report.
|
22293892 |
2012 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Association of ARMS2 genotype with bilateral involvement of exudative age-related macular degeneration.
|
22809783 |
2012 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
GWASCAT |
Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.
|
22705344 |
2012 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The association of age-related maculopathy susceptibility 2 polymorphisms with phenotype in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.
|
21541271 |
2011 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To investigate whether the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2) has a different hereditary contribution in neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).
|
22219653 |
2011 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To compare the genomic contribution of the ARMS2/HTRA1 region of chromosome 10q26 to typical neovascular age-related macular degeneration (nAMD) (also known as typical exudative AMD) and to polypoidal choroidal vasculopathy (PCV) METHODS: DNA samples were prepared from 84 patients with typical nAMD, 181 patients with PCV, and 276 control participants.
|
21191724 |
2010 |
Exudative age-related macular degeneration
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
To investigate the effect of single nucleotide polymorphisms (SNPs) and haplotypes in the genes encoding age-related maculopathy susceptibility 2 (LOC387715/ARMS2) and high-temperature requirement A-1 (HTRA1) in a case-control study in a Chinese cohort of individuals with exudative age-related macular degeneration (AMD).
|
19491722 |
2009 |