Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0456909
Disease: Blindness
Blindness
0.030 GeneticVariation phenotype BEFREE The polymorphism rs10490924 (rs10490924" genes_norm="387715">A69S) in the age-related maculopathy susceptibility 2 (ARMS2) gene is highly associated with age-related macular degeneration, which is the leading cause of blindness among the elderly population. 29316486 2018
CUI: C0456909
Disease: Blindness
Blindness
0.030 GeneticVariation phenotype BEFREE It lies next to the ARMS2/HTRA1 genes in a region of chromosome 10q26, where single nucleotide variants have been strongly associated with age-related macular degeneration (AMD), the commonest cause of blindness in Western populations. 27416785 2016
CUI: C0456909
Disease: Blindness
Blindness
0.030 GeneticVariation phenotype BEFREE Age-related macular degeneration (AMD), a complex multigenic disorder and the most common cause of vision loss in the elderly, is associated with polymorphisms in the LOC387715/ARMS2 and HTRA1 genes on 10q26. 18535016 2008