C1QL3, complement C1q like 3, 389941

N. diseases: 27; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.040 GeneticVariation disease BEFREE It appears that the decreased levels of CTRP3 and especially CTRP13 were associated with increased risk of T2DM and CAD. 28033351 2016
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.020 GeneticVariation disease BEFREE It appears that the decreased levels of CTRP3 and especially CTRP13 were associated with increased risk of T2DM and CAD. 28033351 2016
CUI: C0028754
Disease: Obesity
Obesity
0.030 AlteredExpression disease BEFREE Lower circulating levels of CTRP12 and CTRP13 in polycystic ovarian syndrome: Irrespective of obesity. 30540803 2018
CUI: C0679427
Disease: myeloblastosis
myeloblastosis
0.010 Biomarker disease BEFREE Mutation of K100 significantly reduces the affinity of MoCdc5-DBD to a Cdc5-binding element but not to a conventional myeloblastosis (Myb) domain-binding element, suggesting that K100 is a key residue of the high binding affinity to Cdc5-binding element. 31652438 2019
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease
0.010 AlteredExpression disease BEFREE Our aims were to examine whether the plasma levels of CTRP13 are (a) increased in patients with NAFLD; (b) associated with metabolic dysregulation, obesity, liver enzymes, and dyslipidemia; and (c) associated with putative symptoms of NAFLD. 30247335 2019
CUI: C0028754
Disease: Obesity
Obesity
0.030 AlteredExpression disease BEFREE Our aims were to examine whether the plasma levels of CTRP13 are (a) increased in patients with NAFLD; (b) associated with metabolic dysregulation, obesity, liver enzymes, and dyslipidemia; and (c) associated with putative symptoms of NAFLD. 30247335 2019
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias
0.010 AlteredExpression group BEFREE Our aims were to examine whether the plasma levels of CTRP13 are (a) increased in patients with NAFLD; (b) associated with metabolic dysregulation, obesity, liver enzymes, and dyslipidemia; and (c) associated with putative symptoms of NAFLD. 30247335 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.010 Biomarker phenotype BEFREE The proangiogenic activity of C1ql1/Ctrp14 and C1ql4/Ctrp11 provides novel insights into the new opportunities for therapeutic intervention by targeting C1QLs in tumorigenesis, tissue regeneration, and recovery of ischemic heart disease. 27734226 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.040 Biomarker disease BEFREE These findings demonstrate a novel regulatory mechanism by which C1ql3/BAI3 signaling causes an impairment of insulin secretion from β-cells, possibly contributing to the progression of type 2 diabetes in obesity. 30228187 2018
CUI: C0042373
Disease: Vascular Diseases
Vascular Diseases
0.010 Biomarker group BEFREE Together, these results suggest that CTRP13 preserves endothelial function in diabetic mice by regulating GCH1/BH4 axis-dependent eNOS coupling, suggesting the therapeutic potential of CTRP13 against diabetic vasculopathy. 31676569 2020
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.010 AlteredExpression disease BEFREE We found that the serum CTRP13 levels were decreased in patients and rats with CRF and were negatively associated with calcium deposition in the abdominal aorta. 31145871 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.040 Biomarker disease BEFREE We sought to investigate circulating CTRP1, CTRP9, CTRP12 and CTRP13 concentrations in persons with type 2 diabetes mellitus (T2DM), with age and BMI matched controls, and to examine the effects of a 2 hour 75g oral glucose tolerance test (OGTT) on serum CTRP1, CTRP9, CTRP12 and CTRP13 levels in persons with T2DM. 28207876 2017