LBP, lipopolysaccharide binding protein, 3929

N. diseases: 156; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Patients with radicular low back pain (radicular LBP, sciatica) frequently describe their pain as "shooting" or "radiating". 31651576 2020
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE The muscle onset delays identified between the two LBP sub-groups suggests that pain may not be the primary factor in alteration of APA response. 31726292 2020
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Subgroup analysis revealed a smaller effect size for pain catastrophizing/fear of movement and pain thresholds in individuals with LBP. 31764166 2020
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE The present study suggests that there is a strong relationship between pain severity, FABQ scores, and functional disability in Mexicans with chronic LBP. 28743357 2019
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Minimally invasive RF ablation of the BVN demonstrated a significant improvement in pain and function in this population of real-world patients with chronic vertebrogenic-related LBP. 31115683 2019
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Although perceived physical overload at work was not associated with pain intensity in patients with chronic LBP at 6-month follow-up, we identified a significant association between perceived physical overload related to postures of the trunk and positions of the arms with disability at 6-month follow-up. 31053939 2019
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Sensory changes indicative of increased/decreased central processing of pain and nociceptive input presented differently between individuals with acute LBP and were related to factors such as sleep and alcohol. 29597080 2018
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Whether alterations in lower back loads in patients with non-chronic LBP are in response to pain or preceded the pain, the long-term exposure to abnormal lower back mechanics may adversely affect spinal structure and increase the likelihood of further injury or pain. 28712541 2018
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE It remains to be determined if these results hold for patients with severe LBP and psychological symptoms or whether symptom severity may be associated with pain inhibition deficits. 29030287 2018
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Statistically lower scores were found in the group with LBP for the following SF-36 domains: physical functioning (p <  0.001), physical role (p = 0.015), pain (p = 0.001), general health perceptions (p = 0.015), vitality (p <  0.001) and mental health (p = 0.001). 30657083 2018
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE In the short term, core stability exercise was more effective than general exercise for decreasing pain and increasing back-specific functional status in patients with LBP. 27849389 2017
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Cumulative risks of both leg pain and LBP recurrence were generally lower in participants achieving complete initial resolution of pain post-discectomy. 27584678 2017
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE However, a more accurate estimate of the effect will require further rigorously designed large-scale RCTs on chronic LBP for improving pain and disability. 28804504 2017
CUI: C0030193
Disease: Pain
Pain
0.100 Biomarker phenotype BEFREE Chronic LBP pain is associated with lifetime myocardial infarction [odds ratio (OR) = 2.69, 95% confidence interval (CI) = 1.35-5.36], other coronary heart diseases over a lifetime (OR = 2.58, 95% CI: 1.69-3.93) and in the last two years (OR = 2.19, 95% CI: 1.33-3.60), while there was a borderline association with myocardial infarction in the last 2 years (OR = 2.64, 95% CI: 0.98-7.12). 27171210 2016