LBP, lipopolysaccharide binding protein, 3929

N. diseases: 156; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 AlteredExpression phenotype BEFREE The data of 118 patients with T2DM were obtained from two previous clinical studies, and were retrospectively analyzed regarding the clinical parameters associated with bacterial translocation defined as detection of bacteremia and levels of plasma lipopolysaccharide binding protein (LBP), the latter of which is thought to reflect inflammation caused by endotoxemia. 31536546 2019
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype BEFREE Studies showed that the endotoxemia-related biomarker, lipopolysaccharide-binding protein (LBP), is associated with obesity and fatty liver. 30458048 2018
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 AlteredExpression phenotype BEFREE We report here for the first time the reduction of plasma LPS-binding protein (LBP) levels, a marker of endotoxemia, after pomegranate consumption in newly diagnosed CRC patients. 29770393 2018
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype BEFREE Furthermore, endotoxemia (LBP) was negatively correlated with serum testosterone but positively correlated with IL-6. 29183872 2018
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype BEFREE Our results suggest that OSA severity contributes to metabolic endotoxemia in patients with OSA independently of obesity, and that LBP might represent a contributing factor promoting early atherosclerosis in such patients. 29137477 2018
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype BEFREE LBP, an endotoxemia associated protein might be used as an inflammatory biomarker of both infectious and non-infectious origins in HCV-infected subjects. 28107471 2017
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype BEFREE Correlation analysis revealed that ileal passage of LPS, IAP activity, Proteobacteria levels and hepatic <i>aoah</i> gene expression correlated with serum LPS and LBP, suggesting that ileal mucosal defense impairment induced by WD feeding contribute to metabolic endotoxemia. 28400412 2017
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
0.270 Biomarker phenotype RGD Induction of hepatocyte lipopolysaccharide binding protein in models of sepsis and the acute-phase response. 8418776 1993