LBP, lipopolysaccharide binding protein, 3929

N. diseases: 156; N. variants: 7
Disease: Fatty Liver Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 Biomarker disease BEFREE Serum LBP concentration was significantly increased in nonalcoholic steatohepatitis (NASH) patients as compared with nonalcoholic fatty liver (NAFL) subjects and was correlated with steatosis (<i>r</i> = 0.38, <i>P</i> < 0.0001) and ballooning scores (<i>r</i> = 0.23, <i>P</i> = 0.01), but not with the severity of lobular inflammation or fibrosis. 28216979 2017
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 GeneticVariation disease BEFREE Interestingly, patients harbouring the TM6SF2 rs58542926 T allele that predispose to NAFLD/NASH had higher LBP level. 28464257 2017
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.030 AlteredExpression disease BEFREE NAFLD patients have elevated plasma levels of LBP and they are further increased in patients with NASH. 18000721 2007