LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Insulin Resistance ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Therapeutic phenotype CTD_human Small-molecule inhibitors of PKR improve glucose homeostasis in obese diabetic mice. 24150608 2014
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype CTD_human Small-molecule inhibitors of PKR improve glucose homeostasis in obese diabetic mice. 24150608 2014
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype RGD Generation of leptin-deficient Lepmkyo/Lepmkyo rats and identification of leptin-responsive genes in the liver. 23800849 2013
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype RGD The passive coping Roman Low Avoidance rat, a non-obese rat model for insulin resistance. 19296906 2009
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype CTD_human Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. 11342529 2001
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Therapeutic phenotype CTD_human Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. 11342529 2001
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Biomarker phenotype CTD_human Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro. 10753628 2000
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.500 Therapeutic phenotype CTD_human Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro. 10753628 2000