LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Disease: Diabetic Nephropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.310 Biomarker disease CTD_human Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates kidney injury in murine models of obesity and diabetes mellitus. 29988851 2018
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.310 Biomarker disease BEFREE Black and tan, brachyury (BTBR) mice deficient for the leptin receptor (ob/ob) develop many of the pathological features of human DN and, remarkably, treatment with exogenous leptin ameliorates hyperglycaemia, albuminuria and glomerulosclerosis. 25034792 2014