LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Disease: Hyperlipidemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.330 GeneticVariation disease BEFREE We investigated the associations of <i>LEP G2548A</i> and <i>LEPR Q223R</i> polymorphisms with statin-induced creatine kinase (CK) elevation among Chinese patients with hyperlipidemia. 29296187 2017
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.330 GeneticVariation disease BEFREE Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia. 26984935 2017
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.330 Biomarker disease BEFREE In this study, we examined the differences in leptin, leptin receptor, total cholesterol, and triglyceride levels between healthy dogs and dogs with cholelithiasis, and evaluated the correlation between leptin and hyperlipidemia. 29088261 2017
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.330 Biomarker disease CTD_human Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats. 25222487 2014