LIMK2, LIM domain kinase 2, 3985

N. diseases: 44; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE We also identified TWIST1 as a direct substrate of LIMK2, which uncovered the molecular mechanism of LIMK2-induced malignancy. 30716360 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE Limk2 deletion increased colon tumour size in a colitis-associated colorectal mouse cancer model. 23585469 2014
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker group BEFREE LIMK2 inhibition or ablation is therefore an alternative approach for modulating Aurora A deregulation in cancer. 22492986 2012