FADS1, fatty acid desaturase 1, 3992

N. diseases: 125; N. variants: 32
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.220 Biomarker disease BEFREE A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice. 27832159 2016
CUI: C0028754
Disease: Obesity
Obesity 		0.220 GeneticVariation disease BEFREE There is evidence that obesity and obesity-related phenotypes are associated with variations in several genes, including NEGR1, SEC16B, TMEM18, ETV5, GNPDA2, BDNF, MTCH2, SH2B1, FTO, MAF, MC4R, KCTD15, SCG3, MTMR9, TFAP2B, MSRA, LYPLAL1, GCKR and FADS1. 21796137 2011
CUI: C0028754
Disease: Obesity
Obesity 		0.220 Biomarker disease RGD Effect of simvastatin on desaturase activities in liver from lean and obese Zucker rats. 8446010 1993