LOX, lysyl oxidase, 4015

N. diseases: 328; N. variants: 14
Disease: Menkes Kinky Hair Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022716
Disease: Menkes Kinky Hair Syndrome
Menkes Kinky Hair Syndrome 		0.230 AlteredExpression disease BEFREE Lysyl oxidase activity was also decreased in MD-MSCs during osteoblast differentiation. 26347346 2015
CUI: C0022716
Disease: Menkes Kinky Hair Syndrome
Menkes Kinky Hair Syndrome 		0.230 Biomarker disease MGD Lysyl oxidase is required for vascular and diaphragmatic development in mice. 12473682 2003
CUI: C0022716
Disease: Menkes Kinky Hair Syndrome
Menkes Kinky Hair Syndrome 		0.230 AlteredExpression disease BEFREE Lysyl oxidase (EC 1.4.3.13) is an extracellular copper enzyme with deficient activity in Menkes disease. 8980283 1997
CUI: C0022716
Disease: Menkes Kinky Hair Syndrome
Menkes Kinky Hair Syndrome 		0.230 AlteredExpression disease BEFREE We report here that the amount of lysyl oxidase mRNA, as studied by Northern blotting, and the number of lysyl oxidase mRNA molecules per picogram of RNA, as determined by a quantitative PCR method, were decreased in three cultured skin fibroblast lines from patients with the Menkes syndrome and two from patients with the occipital horn syndrome compared with four control cell lines. 8638917 1996