LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE We aim at exploring the potential relationships of apolipoprotein A (APOA) and apolipoprotein C (APOC) family members with HCC. 31211449 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE Lipoprotein (a): a promising prognostic biomarker in patients with hepatocellular carcinoma after curative resection. 30271176 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease CTD_human Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. 28284560 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE Lipoprotein(a) in patients with hepatocellular carcinoma and portal vein thrombosis. 27822883 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE ATX and LPA receptors merit consideration as therapeutic targets of HCC. 27583415 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE Pharmacological inhibition of LPA receptors with Ki16452 significantly attenuated LPA-induced HCC cell invasion. 23569130 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 AlteredExpression disease BEFREE ATX transcripts and LPA receptor type 1 (LPA1) protein are elevated in HCC compared with normal tissues. 21102517 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE PDI A6 and Apo A-I are closely related to vascular invasion feature of HCC. 21649721 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE Recent studies have identified apolipoprotein(a) [apo(a)] kringles LK68 and LK8 (LKs) as having a potential antiangiogenic and anti-tumor activity, and the current study evaluates the therapeutic potential of gene therapy with recombinant adeno-associated virus carrying genes encoding LKs (rAAV-LK) in the treatment of hypervascular HCC. 16628632 2006
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.390 Biomarker disease BEFREE Interaction of a recombinant form of apolipoprotein[a] with human fibroblasts and with the human hepatoma cell line HepG2. 8728315 1996