LRP2, LDL receptor related protein 2, 4036

N. diseases: 254; N. variants: 51
Disease: Vitamin D Deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.330 GeneticVariation disease BEFREE Haplotypes of GC and LRP2 genes shown significant associations with 25(OH)D levels among pregnant women, respectively. 29153269 2018
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.330 Biomarker disease BEFREE These features are consistent with osteomalacia (softening of the bones) as a consequence of hypovitaminosis D and demonstrate the crucial importance of the megalin pathway for systemic calcium homeostasis and bone metabolism. 12475886 2003
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.330 Biomarker disease CTD_human Megalin-/- mice are unable to retrieve the steroid from the glomerular filtrate and develop vitamin D deficiency and bone disease. 10052453 1999
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.330 Biomarker disease BEFREE Megalin-/- mice are unable to retrieve the steroid from the glomerular filtrate and develop vitamin D deficiency and bone disease. 10052453 1999