|
melanoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Systems analysis of barrier molecule and ARNT-related gene expression regulation in melanoma.
|
31741768 |
2019 |
|
melanoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
In contrast, the cytoplasmic expression of HIF-1β was higher in primary cutaneous melanoma than in intradermal nevi (p=0.001).
|
31594284 |
2019 |
|
melanoma
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
In supplementary meta-analyses derived from genome-wide association studies, one additional locus located 11 kb upstream of ARNT (chromosome 1q21) showed genome-wide statistical significance with CM.
|
25407435 |
2015 |
|
melanoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
The associated variants at the 1q21.3 locus span a region with ten genes, and plausible candidate genes for melanoma susceptibility include ARNT and SETDB1.
|
21983785 |
2011 |
|
melanoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
In a discovery cohort of 1804 melanoma cases and 1026 controls, we identified loci at chromosomes 15q13.1 (HERC2/OCA2 region) and 16q24.3 (MC1R) regions that reached genome-wide significance within this study and also found strong evidence for genetic effects on susceptibility to melanoma from markers on chromosome 9p21.3 in the p16/ARF region and on chromosome 1q21.3 (ARNT/LASS2/ANXA9 region).
|
21926416 |
2011 |
|
melanoma
|
0.370 |
Biomarker
|
disease |
CTD_human |
The associated variants at the 1q21.3 locus span a region with ten genes, and plausible candidate genes for melanoma susceptibility include ARNT and SETDB1.
|
21983785 |
2011 |
|
melanoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
Recently, we identified TANGO as a tumor suppressor in malignant melanoma.
|
17786351 |
2007 |
|
melanoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
TANGO is a tumor suppressor of malignant melanoma.
|
17044017 |
2006 |
|
Colorectal Carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
Here, we demonstrate that ARNT protein levels were decreased in late-stage human colorectal cancer using immunohistochemical analysis.
|
25839165 |
2015 |
|
Endometriosis
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis suggested that the polymorphisms of AhR Arg554Lys and ARNT Val189Val are not associated with endometriosis, while the AhRR Pro185Ala polymorphism may be associated with endometriosis risk.
|
26101050 |
2015 |
|
Colorectal Carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
A strong positive linear correlation was also found between hClock gene expression and ARNT, HIF-1α and VEGF expression in human CRCs.
|
23970287 |
2013 |
|
Endometriosis
|
0.330 |
Biomarker
|
disease |
CTD_human |
Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis.
|
22138541 |
2012 |
|
Colorectal Carcinoma
|
0.330 |
Biomarker
|
disease |
CTD_human |
This study suggests that the genomic region around ARNT rs12410394 may harbor variants associated with CRC.
|
21081473 |
2011 |
|
Colorectal Carcinoma
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
This study suggests that the genomic region around ARNT rs12410394 may harbor variants associated with CRC.
|
21081473 |
2011 |
|
Endometriosis
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Odds ratios and 95% confidence intervals were calculated for AhR, ARNT, and AhRR genotypes to evaluate the risk of endometriosis.
|
16084889 |
2005 |
|
Endometriosis
|
0.330 |
AlteredExpression
|
disease |
LHGDN |
In conclusion, the female reproductive tract expresses mRNA for the transcription factors AHR and ARNT, and changes in their expression at select target sites in specific pathological conditions such as endometriosis and uterine leiomyomas suggest a potential role for these factors in the pathogenesis of these conditions.
|
11756572 |
2002 |
|
Endometriosis
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, the female reproductive tract expresses mRNA for the transcription factors AHR and ARNT, and changes in their expression at select target sites in specific pathological conditions such as endometriosis and uterine leiomyomas suggest a potential role for these factors in the pathogenesis of these conditions.
|
11756572 |
2002 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.310 |
Biomarker
|
disease |
CTD_human |
Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia.
|
22674224 |
2012 |
|
Miscarriage
|
0.310 |
Biomarker
|
disease |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.310 |
PosttranslationalModification
|
disease |
LHGDN |
The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.
|
16410262 |
2006 |
|
Miscarriage
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
The aryl hydrocarbon receptor nuclear translocator gene polymorphism in patients with recurrent miscarriage.
|
16364012 |
2006 |
|
Childhood Acute Lymphoblastic Leukemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
We identified significant associations of childhood ALL risk with haplotypes of ABCB1, ARNT, CYP2C8, CYP1A2, CYP1B1, and IDH1.
|
22674224 |
2012 |
|
L2 Acute Lymphoblastic Leukemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia.
|
22674224 |
2012 |
|
Liver Cirrhosis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice.
|
22271822 |
2012 |
|
Fibrosis, Liver
|
0.300 |
Biomarker
|
disease |
CTD_human |
Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice.
|
22271822 |
2012 |